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Prolotherapy and PRP Injection Therapy | Scottsdale & Phoenix

Regenerative therapies, including prolotherapy, platelet-rich plasma (PRP), and stem cells, can often eliminate joint pain.

Every joint in the body has ligaments, tendons, and cartilage that can be injured. We specialize in managing pain and restoring musculoskeletal function. Regenerative medicine can benefit anyone with joint pain, helping your body rebuild healthy structural tissue and restore full pain-free function.

Regenerative treatments are less invasive, less costly, deliver quicker results, and require minimal recovery time. Elite athletes and active people take advantage of these non-surgical regenerative treatments to get back in action faster and stronger, and to prevent small injuries from becoming more serious.

  • Prolotherapy is highly effective for joint pain management. To stabilize the joint capsule, rebuild collagen, strengthen and repair ligaments and relieve pain, injured tissues are infused with a nutrient solution of glucose, vitamin B12, and lidocaine; glucosamine may be added to increase stimulation. Generally, 3-6 treatments provide full resolution; the number of initial treatments and annual tune-up treatments that our prolotherapy doctors recommend varies depending on the individual and the severity of the damage.
  • Platelet-rich plasma (PRP) therapy concentrates your platelets and their related healing factors so they can be injected directly into ligaments and joint tissues to heal moderate to severe joint degeneration, cartilage tears, and arthritis damage. PRP therapy treatments provide stronger healing stimulation than prolotherapy. When pain is combined with joint inflammation, we often start with 1-2 prolotherapy treatments, followed by 2-3 PRP treatments.
  • Stem cell therapy heals injured joint tissues, degenerative joint conditions and musculoskeletal disorders, including osteoarthritis. The stem cells and their associated growth factors are extracted from a patient’s own adipose (fatty) tissue. Stem cells will develop into bone, cartilage and tendon cells as needed, generating new tissue to replace what’s been damaged. The growth factors decrease inflammation, manage pain, kill microbes and trigger the growth of new connective tissue and blood vessel cells.

Healthy ligaments are key to pain-free joint movement, yet ligaments are often missing from orthopedic evaluations. Our physical exams identify injured ligaments, which are often the targets for effective treatment.

We work out a plan for the number and sequence of treatments that will deliver the most effective solution for your pain management. Our exams explore for indirect factors too, like stress, environment, and diet that may aggravate a physical injury. Our treatments apply a progression beginning with the simplest, prolotherapy. Where we want a stronger effect, we use your own blood cells to make platelet-rich plasma (PRP). For serious or advanced cases, we will use your own stem cells to rebuild healthy tissue.

These pain management and regenerative therapies concentrate your body’s own healing compounds to stimulate natural healing processes, accelerating repair of damaged joint tissue, rebuilding healthy tissue and restoring full function. To treat more serious conditions, our PRP and prolotherapy doctors may offer nutrient infusions and detoxification at our Scottsdale clinic serving the greater Phoenix area.

“Went to doctors here several years ago for knee issues. Had several treatments for strengthening the knees. I am very satisfied with the results. I would recommend their treatment instead of surgery.” — Sam R.


“The best sports mainstream doctors and surgeons couldn’t help me. They told me that the torn tendons in both of my big toes wouldn’t heal, and I would not get rid of the pain. Vicoden did nothing for the pain. I was going to have to quit dance and still be in pain just in normal day-to-day activities.

Prolotherapy at NPG was my last option, that I thankfully heard about from an occupational therapist friend. It’s been almost a year, I am almost totally pain-free, and I am dancing and competing on my toes in dance. I take no pain medications at all. My entire quality of life is back!” — Colette M. 

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